====== FASTA of the second type of P450 sequences lacking the conserved Cys ======

Type 2: Mito clan, Hemipteroids (16 sequences)
Species / taxonomic position and accession number
(from Dermauw et al. 2020, Suppl. File S2) 

%%>%%Aquarius_paludum-Hemiptera-Gerroidea-GDFO01070937
MESIINTKNSEKLSDKYHLSKLDE
AKILSKPFPVDAIDPLSIPGYTPSLSEKPILPKDFIKFTAPATITSYDLVPGPSLLKTVG
NIWKYIPLLGTQFVATLIYSMQSLISSYDRRLKYPNVYPYYYLLNKYGPMVRLHGPIGAD
ILVMAVNGLDFPLVHIKTRANKRQSLFDSLNTYRRDATPLSYMLNFPKASLRIPDNPTLK
IDHHYSSLERITDDFINRRKFVRTYTGAKDDDSHGNDLLKWAMQCTMDVYFKSKRDYMEQ
SGSESSKIVDSFIKASKSVRLCETGIQLWRAFTTLTWLDLAEYCKEMDRFIVNEVSQCMT
RSSQGKTNGSVVELLLASEELRTTDLLTPLLDLLIINVNMAATTAGFLLYNLSKTPQVQR
TLFREVSSVLPKGKGNINQSDLAKLKYLNACITETLRMVPPFPVLSRQIEEDTKIHSFQI
PKGTYVQMVNVLPCARGDVCYDDIGRFQAERWTDKTTSLGGDPLLGLPQWQSAPKFNRDL
IITQVALLVAKVVREYRIEYPTADVFSDGMVLQGPTTPFNFAFIERVI

%%>%%Buenoa_margaritacea-Hemiptera-Nepomorpha-GCXE01028779
DNLLISTSVRRELV
YRPLARSPAYSVPFDHLPGPNALKVLGKLFNCVPMATSQLTIASVNQVHHVTHRMGKKME
SLSGYSPYSVLFSKFGPLVRLSGLLGGEVVLVKADSHTRNVISTLASESSTYTSLFDSLE
AYHRIKNPSHFVSSPCKESDWDILNAKYKDGREFQPEEVFQLQETLTEELIQKTHSMRNS
YNEVNDEFRTSIMRWGIECVGRGVSEETGLCSPDVDRLVNPLMAASESLAHCETGLQFWR
MMSTPAWNKLVDSCSVLEGLLNWQLKDGLRRLGKKSSGSELVTCPSVEMDLGRSHTSPQQ
VLSKVLDTYLVRVNMGVNLSCFTMYNLAKNPRCQSQLFKEIKDKIPDKDIEIEPKVIMDM
KYLMGCILETVRLNNPFPVTIKLLDKDIVLQGHKIPRGTHVVMASDVTICDGEKYERPDA
FAPERWLEAPTPDQQSQLPLEEGPLALCPFPGHHDRLLTYQQIALLVVKMMQHFVIDYSD
TQVSSRNSFLAMPDKSFKFRLTERK

%%>%%Chauliops_fallax-Hemiptera-Lygaeoidea-GCXK01007253
MKRQGIILSSRQGLPLSRSVHGPLGSVRAVEMQTAALSVTTNWWRRRRTEAVYVLPL
EAVPGPSWKLGSLADLLAQGTTASYLASRYGPLVRLPGPRLIASHPPHIQSLLAASRPDR
SPLPTMEEKRNVTLPVRMPEYEHDFSSLTVKYNGQLDFKQNHFNSIIEEASDILIERMHY
FKNLQNEVPRFKDELYKWSLQCTFGILFSKDFGFLEDVTVMNEHDIRISSAVQIFSILKE
ASVCLVESESGPLGKFFHKRTFENHIDVLHGVLCRHLRVKYLSLVRDPPKKLGLVEKMVL
REKMSANDILNRILDIVVLGVNVVVNSVGFIIYHLSKYPGCQGKLLDEVSTYHLSNLQEL
PYLNCCLAESMRLRPPFPSLWRETDADVIIHGYGIPRRTPICLLNEIANMREELFPRPSE
FSPERWELKSGRPLSYEYNLLPMARVAPLLHAQMAILTAKLTKEFKFEYHCGSIESGGRA
LAAPNKQFSFTFI

%%>%%Cimex_lectularius-Hemiptera-Cimicoidea-XP_014255591-CYP394A1
MLRIKLIQRLFSLIKRKTTYTATTSPTTSEEQPTSKVLASNVEEEAELDERLGTDDLFFASEHLPFTVMQQHEQIFPKAKPTLLDPLIDETQRVDKSGVCAVPFSQIPAIGGHLWLELCHLFSKCLYAIKGQNDEKLLSWIYPFRIFFDFYGPLVRINTPSKSSVVMLCKPKHILAVQKYDGTHSLRSIIDSMENYRRTRISITMPQYEIDFSQVAEKFKNHLNHRVNDYQYLCNQMAVDFVKRNYLIRDHRCEVPANYNGELCLWSLKCFSAIVFGRDAEYKQDGYTKIVHTLIEVSKALSDCESAPQIWRFLPTTSTSKLAQCFDVLETLLIRNLRMTYLKLGKLSKNVKNETPQPVALLETMILKDKMSTDCIITTLMDLLVVGVNSIANIAGMVLYYLSKSPDVQDRLFWEINLVIPHDLNELFSEDMIHLPLLRACIVETMRLWPPFTHTVRCTSKEIVVNGYTIPKNTNVIMAHQIAFHKNEHFADAKKFEPRRWIGRFSKQLDPLEVMPFCHRQHPIIKELAYRQIAVLIAHMVKNFEIEYNYGEMSYESKILSLPSKPLKFTLKDRH

%%>%%Gelastocoris_oculatus-Hemiptera-Nepomorpha-GCXI01030921
MDGLTMMRRWQQLGRMGAIMVRGMADLAKNAENAQLTPKRTDHNRIKGAPLPTTKGP
IPEENLQTDSLLLTPAAAPKPKSPHIFRTTSPKASMSSAVGGPMPSGAADGEGVSGGSAK
PFMPAVVSQTEESAVTPFKKPQLAMVDKEPRTAVMPFTDIPGPAVFTWINQFWQYLPALD
GRFKWVYKVRPYKMLFDEYGPVVRLHGPFGGDIVLLNRPEDIKSLYDQDVRPEGHSILDS
LDAYSKFKCQNDINPINAVEFPQLTEKFSDSLEKNLEDFHGAMDQSADELVSMLYVRRNV
HEESPTFNQELYKWSLKSMIRTLFDKEASQDTSMCDMTATICVKPLLEASEALGSCECGV
QLWRFIPTPSWNQMSNSCDLLMGLLCQNIHAAYMKLEKAKEAARGEMKLSFAESLILKGQ
LTPEHMLTKVLDTILVNVNASVNAAGFLMYHLARNPLSQKRVFEEVSSVLPSKDGPLMFD
PEFANLKYLNACFTESLRLSPPMPFSTRVLSNDVVIRGYSIPKDTLAILSHESPCQVDDK
FYQPDRFSPDRWLEGENGCDAGDLLASVPSHDPLLRQVIHHQAITLVAKVVRNFTLEYNY
GPIVRAGNRMFEIPDKLFKLSFVEREQ

%%>%%Halyomorpha_halys-Hemiptera-Pentatomoidea-GEDY01046576
MRYRNVFRGIYAKRSIFKGIPRNSYLAHLRSVRKTLLQRIEVDQFARSQ
KEEVYVLPFDEIPGPKVPSFIPSKYIVGPIQQAHSTGWFQPYEMLFTRYGPLVRVNGDSL
LVSHPRYIEAIMAISLPNRSALSTMERKRRLSLPIRMPEYELDFTELSEKYADLLNFKPN
HFNKRIEVASDQLISRMYYTRNLQHEVPNFDEELYQWGLQSMFCCLFSRDCTFLQDPIGN
NEFGPKSGIYQTYQTFLNASYCLAEAEAGPLGRLVRQHSVANHIDVMNGILCRNLRTKYL
ALWRDTDKELQTDLVEAMILRDKMNSNDILTRLCDIVILGVNIVAHSVGFLIYHLAKSPV
YQPMLHEAVMKADSDNLHCIDFMNYCIYESMRLIPPFPSLSRDLDRDIILHGYGIPKGIQ
VHMINEVANMRKDMFPQTTVFSPERWPRMGKEPMLPHNYQLLPLAPVAPLLHAHVSVLTA
KLVKHFKFEYHYGEIKSGQLLAKPNKPFLFTFIDRDREGIPVTTK

%%>%%Largus_californicus-Hemiptera-Pyrrhocoroidea-GCXR01047327
NTSFTLIYFPLINSFFPFLNPMLLIQAKYFLTNNYSIFRNKYYLNHAICRFMPRRILTSTVCSTSEDFLIRTQPEQVFVLPFDKIPGPNLPHWLPSRWVIGPIQQAHTSGKEWIKPFERLFARFGPLVKLDGDTLLASLPRHIEKILTASRPNRSSLSVMESKRKQTLPVRMPEYDTDFSYLSTKYSSHLDFKPDHFHSIIDGSSDKLIARMVYFRNLQxEVPHFNDELYKWGLQCMLGCLFSKDFCFLEDVSKQIDCDSLNSGAAQILGTFKGAAQCLAEAEAGPIGKFLKQHIFEDHIDVLHGILCRQVRIKYLSLAREPPSKLGLVEEMILKKKMSANDILTKLLDTIILGVSIVAHSVGFMIYQLTKYPGCQGKLFDELSTYHLSNVQDLPYLKCCVAESMRLRPPFPYISRELDDDVIIHGYGIPRGTHVYLINEVAYMRKELFPRPKEFSPERWELKSGRPLSYEYHLLPMTSIAPLLRVQIDILIAKLAKKFKFEYHYGKISSYGRVLATPSAPFRFTFIDRKP

%%>%%Murgantia_histrionica-Hemiptera-Pentatomoidea-GECQ01183933-CYP3221A1
MRYRNVFQEVNAKRSIFKGMPWSSYLGQLRPLQKSLLQAIEVDQFARSQKEEVYVLPFDEIPGPKVPSFVPSKYIVGPIQQAHSTGWFQPYEMLFTMYGPLVRVNGDSLLVSHPRYIEAIMAISRPNRSALSTMERKRRLSLPIRMPEYELDFTYLSKKYADILNFKPNHFNKRIEVASDQLISRMYYTRNLQHEVPNFDEELYLWGLQSMFSCLFSRESSFLQDPTGHHKFGPKSGVYQTYQSFLNASYCLAEAEAGPLGRLVRQRSVANHIDVMNGILCRNLRTKYLALWRDSEKLQADLVEAMILRDKMNSDDILTRLCDVVILGVNIVAHSVGFLIYHLAKSPVYQPTLHESVTKADSDNLHNIDFMNYCIYESMRLIPPFPSLSRDLDRDIILHGYGIPKGIQVHMINEVANMRKDMFPQTRLFTPERWPRMGKEPMLPHNYQLLPLAPVAPLLHAHVSVLTAKLVQHFKFEYHYGDINSGQLLAKPNKPFLFTFIDRSK

%%>%%Oncopeltus_faciatus-Hemiptera-Lygaeoidea-GCXY01042292
MNISPRNHKVLSCLKANNFDLFLKNVESTSR
MQSFVLSNMAVSPGVDDSRVFRRRVEAVYVLPLEAVPGPGWPGRLLFGPISLQLHLAAPG
SLAARYGPLVRLPGPTLLASHPRHIQRLLAASRPDKSALPTMEAKRKDTLPVRMPEYETD
FSHLATQYNGQLDFKPDHFNSIIEEASNNLIERMNYLINLQNEVPCFKDELYKWSLQCTF
GCLFSKDFGFLEDTSLMNEHDIRISGAVQIFSTFKEASRCLVEAEAGPLGKIFKKRTFED
DIDVLHGVLCRHLRVKYLSLSRDPPSKLGLVEKMVLKEKMSANDILNMILETVVLGVNIV
AHSVGFIIYHLSKYPGCQGKLFDEVSTFHLSNLQELPYLNCSIAESMRLRPPFSYLSRDL
DDDVIIHGYGIPRGTQVYLANEIANMREELFPRPNEYSPERWELKSGRPLSYEYHLLPMK
RIAPLLQSQIAILTAKLTQKFKFEYHYGTIGSGGRALATPNKPFSFT

%%>%%Pagasa_sp-Hemiptera-Nabidae-GCXU01023568
MLRIILQLRRSLVLKGRAQLISTNSIPSENDDEQERNEIPGPDDLFFSSEHLPCSVSQPD
EQIFPKAKPTLLDPPVDGAKHVNKSGLCAVSFQEIPSVGGSLWIKFCNATSRYFAGAKVE
PESSLVSWIYPFKKLFDKYGPLIRVITPTRNDVVLLCKPQHILMIKKHDEPHAVRSVIDS
MEHYRRSRLSIKMPQYELDFSKVAEKFKNQLNHRVNDYQLLCNQMALDFVKRIYAIRDHR
FQVSDSYNEELCLWSLKCFSGVVFGRDAESKPDGYTKVVKTLLELCKILGDCESTPQLWR
FVSTPSTSKLSECFDILEALVLRNLRMTYLKLGQMTENDKESSSQPLALLDSMILKDKMS
TDNIITILMDLLVLGVNSTANIAGMVLYYLSKYPEIQDRLFWEINLVIPHDLSELFSEDM
VHLPLLRACIIETIRLWPPFNHTVHCTSKEIIVSGYKIPKYTQVIMAHDIAFHKEDHFAD
AKKFEPRRWVGRFSKQLDPLEVMPFCYRQHPVIKELAYRQIAVLIAHMVKNFEIEYNYGD
IEYDGGRLLLSAASKPLKFTFRDR

%%>%%Panstrongylus_lignarius-Hemiptera-Reduvioidea-GFTR01007413
MSSVFPKAVSTTLERFKTNSKDMVYAVPFDEMPGPSSLRSIANF
YRHIPIISSQLTTLFLNRAQQVGKLPTATGINQEGSWIQSVMSSIRPYDLLFERYGPVLR
LHGPFGGDIVMLSLPEHIETVYNVDSQYPVRALLDSMEVYRKSKVIPNMPSYEGDYELLR
EALKYSLDLKLEDFDTMLEQIADDLIHRISCIRNMQDEVPDNFHKELHKWGLECWSQIIF
NNKVGFLQKNNLSDLSEAGRMLNLLIEASQALRNCESGLQFWRIWPTFSWTKLTSAIDML
EGLLCRNLRVNYIKLSKMNKNAKDVQRLCLMDAMIIKEKLTSDEIITTVLDLLIIGVTSV
SNSAGFAIYHLAKTPRAQTRLLQEIVQFLPSKDSKLFSHNLSNMNYLKSCVLESLRLRPP
FPYTTRCLSKDLVIHGYTVPRGTLLVMANEVAYHKDENFECALRYEPERWMDAFSNPFDP
LAAMPFCHGQTELIKQIAYRQLAILIAKLLRNFKFEYHYGRINQDGKVLAIPKKPFRFRF
VERAE

%%>%%Phymata_pennsylvanica-Hemiptera-Cimicomorpha-GCYI01036023
MSSITPANILFKHFKIKIMINRSFCEKLLELNVNNLKLDEENVMKGAVTNMDIS
AQQLDDLRANNEICEERLNSDDLLITLSRSKGLSSVFPRAPTSLSDFKTDHKDAVYAAPF
DEIPGPSLLKALANVFHYIPMLSTNFTAVFLNKAHQVTKCSVISSGTQLEKAWLPRAIST
LSPYNLLLEHYGPIIRLSNPLGGEVVVLTLPEHISAVYRADGQHPVRAIFDSMETYRKIR
TPSNMPNFDGDYDLMSKKLRINYTEEDFDLLLESVSEELIKRIGSVRNMQDEVPDSFSEE
LHKWGLECWSQYMLNRRIGFLTDSNTSIYSESGRMLKLLIEAGHYLRNCESGLQLWRLFS
TYSWTKLTSAIDILEGLLCRSLRLNYLKLNDISEASNNEEVYNRTCLLDAMIVKDKLTSD
EILTAMIDSLIIGVPSVCNSAGFLMYHLAKNPKVQNRLFNELMEALPTKTSQFQPNQISN
MPYLKACVVESLRLIHPFPYTVRFLSKDMVIYGYSVPRGTLLVMANEIAYHKEEYYENAL
RFEPERWIDADTKINFDPLAAMPFCHSQTEVIKNLAYRQLAVLVAKILRNYKLEYHYGQI
RHDGKVLAIPKRPFRFRFVQREV

%%>%%Plea_minutissima-Hemiptera-Nepomorpha-GDES01037678
MKKTMKNIHCILVIESGLCLAVQRRGISVLPWRQREKEVLTNIA
DSKVIPSLDPPPPHESPGFISEPPTIKEEPPLNTDNLFMAANQHPPPKKILADSKAKACA
SMNLVQSDVKCFASFGELPGPSALKVINKGWSYIPLFGAQSSISVLSHAQGFFNRLGKRF
KWMLRMRPFNYLFEEYGPVVRVGTILGGDVVLIKRSEEVRSLIQSLDTPTGSSSLVDSLE
NYRKWKLPAPLPLSFTDGQGDKSWLKLEETLQEKLQFKAEDFMSVQEQISDEFIAKIFSE
RTAQEEFTDEFRMNMFKWGLECMSATLFNERQGFMEVGHRGTSVTEASRMLPAFLTASEG
LSACETGLQMWRLLPTKGWNMLTKSCDILEGFLCRNMRASHIKLEKMASGIQDIKNPSLV
QALILNEHLTPEQTLTKLLDIFLIGVNTAVNSASFLLYFLAKYSRVQNKLFKELIESLLN
QGSKFTPEEFKKQKYLMACVIETLRMKTPFPFMIRKLEKDVVLHGYIVPKGTHLLMANIM
ELMSEEKFEEPERFLPERWHLEAPLSVEDDPLAAAPFSNDLTRQIIYQQVAILIAKVVRN
FSLEYHYGPIHCNDHFLCPPNRPFKLRAADRAQ

%%>%%Rhodnius_prolixus-Hemiptera-Reduvioidea-GAHY01000067-CYP394B1
MFKVGTIFSTLFASCFRWFKKLLSGILLFRRSSKDFLRNAVVDNIYVKTQPTSEIRQGTQIPKTCTEANNANIDTAEERLGTDDLLLTISKSKMSSVFPKAVTATLERFKTNSKDVVYAVPFDEMPGPSSLRSIANVYRHIPVISTQLTTLFLSKAQQVGKLSPSTGINQEGSWIQSVMSSFRPYDLLFERYGPVLRLHGPFGGDIVMLSLPEHIETVYNVDSQYPVRALLDSMEVYRKSKVTPNMPSYEGDYELLREALKYSLDLKLVDFDSMLEQIADDLIHRISSNRNMQDEVSDNFHKELHKWGLECWSQLIFNNKVGFLQKNNLSDLSEAGRMLNSLIEASQALRNCESGLQFWRILPTYSWTKLTSAIDMLEGLLCRNLRLNYIKLSKMNRNAKDAQRLCLLDAMIIKEKLTSDEIITTVLDLLIIGVTSVSNSAGFVIYHLAKTPRAQTRLLQEILHYLPTKDSKLLSYDLSNMNYLKSCVLESLRLRPPFPYTTRCLSKDLVIHGYTVPRGTLLVMANEVAYHKDENFECALRYEPERWMDEFSNPFDPLAAMPFCHGQTELIKQIAYRQLAILIAKLLRNFKFEYHYGRIHQDGKVLAIPKKPFRFRFVERAE

%%>%%Sehirus_cinctus-Hemiptera-Pentatomoidea-GCZB01036540
KQLKVFFLVVYLYKNLCVFSFCEILMRFRHDLQGIYTKRNLFRGSPKSSYLAIQRSLQKS
LLPNIEVDFYARWQKEEVYVLPFDKIPGPKVPSFIPSKYIIGPIQQAHSSGFHPYERLFA
TYGPLVRVNGDSLLVSHPRYIATILASSRTNRSALSTMERKRRLSLPIRMPEYEMDFTQL
SEKYGEQLNFKHNHFNKYIEVASDQLISRIYYCRNLQHEVPHFSDELYKWGLQSMFSCLF
SRDCGFLQDPTGGKSCKPNSGVTQTYQSFLHASICLAEAEAGPLGRLVCQRSIANHIDVM
NGILCRNLRAKYIELSRNIGNPDKRPDLVEAMILREKMNSNDILTRLCDIVILGVNIVAH
SVGFIVYHLAKNPIYQGTLYNDIARADQSNLNNIDFLNYCIYESMRLRPPFPYLSRDLDC
DIVLHGYGIPRGIQVHMINEVANMHTFPQPKMFMPERWVQMGNDPLLPFNYQLLPLAPVA
HLLHAHISVLTAKLVRHFKFEYHYGKIKSGGQLLATPNRPFIFTFIERNK

%%>%%Velia_caprai-Hemiptera-Gerroidea-GAUO02024238
MEIQRVIDPAKRP
VISDYKPIPLEKPVSPVLPKEFKKFPEEATASAFEAIPGPTVLRSVGNIWKYVPILGTQI
VSTLMYTMQSLATSYDRGMKYPSLNPYHYLLNRYGPVVRLHGPLGADIVLLAVNGQDFPL
VHTKLKGNNYQSLFDSLNVYRRETPPLTTTLLTMNPKTSKMPDNTTLSVDQYYSTIENIT
DDFIKRKKFIKSYSSGEHHTEGQENDLFKWALQCTTEVYLKTGRNYLDDAASNNESNKMS
EYLVRVSKSVKLCETGIQLWRAFTTFTWMDLTEYCKHLDRHIVDEVNRTLQDIKQGKSSG
SVLESLIYTDELRSTDTLTPLLDVLLINVNVAASTAGLVLYNLGRTPQVQRNLLREIGSV
LPKGGKSITRSDLTKLKYLNACITETLRMAPPFPMLSRQLEEDTNINGFDIPKGTYIQMV
NVVACSRGDYAYEDMGRFQADRWTEKEHSKGQVTTPPHTLGGDPLTGLPQWNTCPDFNRD
LVLTQISLLVAKIVRDYRIEYPNYSLHSDGMVLAGSTTPIDLAFTDR