====== FASTA of the third type of P450 sequences lacking the conserved Cys ====== Type 3 - CYP3 clan, Aphidoidea (16 sequences, some obviously partial) Species and accession number (from Dermauw et al. 2020, Suppl. File S2) %%>%%Acyrthosiphon_pisum-XP_008180507m-CYP6YC1 MGAYVTWTLEVLAFAIFVVVAAVVPYARRKRDYWMNRGVLAAAGYRLLVNTLPGIRLHDRSLSGHRNDAKAAGAAVLGLYDAGRPTVLACDIRVAAAAMANDGFAEVETRGGREMSLLPTAVDAGAVTAVLPTMAVCVAELITSLEAVANRRLTIVPWTEVKKCATTVVATCVYGQPMVDSRIKAFAEQCDKALSGASGRPTVTDHFASYDLSSDGRASSSDFKQILRAAAADSDKIDADVADKQVRLDMFEFVTGTIEQTAALVTGALYELARDQNIQNHLREHLDSVLDEHQEQVTIDQLDRLPYLENVLKETLRKYPLAAVVRRVATKPYVVPGTGGRGTIEPDSLIVVPVYELHHDAEHFTEPEKFQPHRFPGQLSSAYMPHGSGPQSYIGKHFVELEAKLVIAMLMSRYEVHVDSATPGTPPDPLDRKSFEGVRMTVANRSSVRESTMGASLRQFHMSNGVNSGDRKFLFF %%>%%Adelges_tsugae-GBJX01012607 MYSTLALESLAFAAFVVIAVLLPYVRRKRNYWTSRGVPVANGQSVLTTLPVCRLDEKALT AYREAAADAPVMGLHDAGKPCALACDVKVASVVLGNDSFVEDDSTSSVAGFSRIPTVLTE DAMYTLAPVMAECVAELVTSMEAIANRRLTVAPRANVKRCATIAVATCVYGQPIIDSQMK TFEDNCEQALQVWRDPVATAKHMSAYEEKTSTNCFKTILCKAANTETVDLEVRSDLFTFV TCAIGSTADLVTAALYELSRDQKTQSLLREHLDSVLDEHSSLITMEQLDQMPYLENVLRE TLRKYPLSPVIRRVAIKPYTVEKLQKSETIDPGVLTLVPVHAYHHDKTHFANPEVFQPHR FPGQLSSAYMPYGSGPQSYIGKNFVSLEAKMIIATLISKYEFNVDSADPGRTPDPFDKSS FAGVKVQLSNRMTRDRTLEESLRQINEKNKLFKLF %%>%%Aphis_craccivora-KAF0772856 RRVATKPYIVPGTSDRCTIEPNSLIVVPVHALHHDAEHFPEPGEFQPHRFPGQLSSAYMPHGSGPQSYIG KHFVELEAKLVVAMLVSRYEVHLDSSNPGTPPDSLDPRSFAGVRLKVVNRSGVRESRMYTSLQQLHNGNN EK %%>%%Aphis_glycines-GBSU01032820 EHLDSELDEHQQQVTIDQLDRLPYLENVLKETLRKYPLVAVVRRVATKPYIVPGINNHCT IEPNSLIMVPVHALHHDAEHFPEPEEFQPHRFPGQLSSAYMPHGSGPQSYIGKHFVELEA KLIVAMLVSRYEVHLDSSNPGTSPDSLDPKSFAGVRLKVVNRSDVREPRMYTSLQQLHKD NNERAGDRKFMFF %%>%%Aphis_gossypii-ATN95984-(formerly known as:)CYP6UN1 MVDSRIKAFAEQCAKALSPAGGGGRPTVTDYFAVYDLSSDGRAPSTDFKQIFRMAAANSDKIDADVADKQVRLDMFEFVTGTIEQTAALVTGVLYELARNQNIQNHLREHLDSELDEHQQQVTIDQLDRLPYLENVLKETLRKYPLVAVVRRVATKPYIVPGTNNRCTIEPNSLVVVPVHALHHDAEHFPEPEEFQPHRFPGQLSSAYMPHGSGPQSYIGKHFVELEAKLIVAMLVSRYEVHLDSSNPGTSPDSLNPKSFAGVRLKVVNRSGVREPRMYTSLQQLHKDNNERAGDRKFMFF %%>%%Cinara_cedri-VVC38578-Aphidoidea; Lachnidae MSGYITVALEVLAFLAFVVMAVGVPYVRRKRGYWTDRGVPVAGGTLATTFPGVRLNERLLTSYFKHATAA VVGLHDAGRPCALACDVRIAASAMGNDGFAEPGYRGAQDGCSLVRTVMDAETMATVMPVMNECVAELVTS LEAVANRRLTIAPWTRVRKCAATAVATCVYGQPMIDSRIEAFAAQCDKALKSPAVITDYFAGYGLSDDDG RAQPPHIKRLLHEASADHHQQQLGSDVNSKRVRSNMFEFVTGSIEPTAALVTATLYELALDQNLQNRLRK HLDGVLDEHQQQITIDQLDRLSYLENVLRETLRKYPLVPVVRRVTTKPYTLPPGSGGRASTLETDTLVVV PVHAFHHDGRHFAAPEAFRPDRFPEQLTVAYMPYGTGPRSYIGKHFVGLEAKLIIAALVSRYEVHLDSET GTPPNPFDVTSFAGVQVMVANRNMRDRESSIEASLKPINDKKFLFF %%>%%Daktulosphaira_vitifoliae-GDEB01018256 LILFTLTILIVSLIRKKRNYWYSRAIPVAKGQSVLSTLPVCRLNEKHLTSYRNIAIETPI VGLHDAGKPCVLICDVQAASIVLSNDGFVEDTEISQAHTHSKIPNVITEDNMQVVMPAMA ECVKELAVSLEGLANRKMTIAPWAALKRCASNTVATCVYGETMIDSRMKAFEELCNVAMK YEKTQTAGKHLISYENALSANCIKTMLCKAANIDIVDDEIRMDMFTFVTKAIEPTAALVT ATLYELSQNSRIQSQLRNQLDEVLDEDLNNLTIEQLDRIPYLDSVIHETLRKYPLMPVIR CIVTKPYSIQTKQKTLTIEPGVVTLIPVHAYHHDKIHFTNPETFHPNRFPGQLSSAYIPY GSGPQSYIGKHFIGLEAKMIVAILLSKYEFTVDKRNPGKAPNPFDKSSFSEFRVQLSSRM ARNCVMEQSLQELSKKNKLFKLF %%>%%Diuraphis_noxia-XP_015372631 MGSYVTWTLEVLAFXIFVVLAVVVPYARRKRDYWTSRGVLTAAGYRSFACTLPGIRLQGRSLSGHLNDAKAAGAAALGLHDAGRPTALACDILVAAAAMSNDGFGEVDARGGHELSLLPSAVHADAVAAVLPTMAMCVAELITSLEAVANRRLTIMPWVELKKCATTVVATCVYGQPLIDSRIKAFAEQCDKALSAGGGRPTVTDYFESYNLSSNGKESFTDLKTILRSAATGSEKIDADVADKQVRLDMFEFVTGSIEQTAALVTGALYELACDKNIQNHLREHLNSVLSEHQKQVTIDQLDRLPYLENVLKETLRKYPLASVVRRVTTKPYVVPGTGGRVTIEPDSLIVVPVHALHHHAEYFPEPDKFQPHRFPRQLSSAYMPHGSGPQSYIGKHFVELEAKLIIAMLVSRYEMLVDSSKPGTSPDPLDPRSFEGVRMTVTNRSGVLESTMCASLRQFQMSKEENAGDRKFLFF %%>%%Essigella_californica-GAZF02034318 MNSYVKGALEVVAFVVF IAMAVGVPYVRRKRSYWTNRALPVAQGHRAMATTLPGVRLDDRSLTNYCKNATASVIGLH DAGRPCALACDVLVAVSAMGNDGFTESEGHGTDDGCSLVPAIMDTETMVTIMPVMNECVS ELVTSLEAVANRRLTITPWTRARKCAATTVATCVYGQPMINSRIEAFAAQCDKALKSSAT ITDYFTGYGLSDDDGRVQTPHIKRFLRKASADKNLGSDETDKRIRLDMFKFVTGAIEPTA ALLTAALYELARDQNVQNRLRQHLDSVLDEHQQRFTLGQLDRLSYLENVLRETLRKYPLV AVVRRETTKPYTLPPGSGGRVCTLETDTLTAVPVHAFHHDSKHFDAPETFRPHRFPEQLT AAYMPYGTGPQSYIGKHFIGLEVKLILAALVSRYEVHLDGEAGTAPDPFDVTSFARVQIM VANRNMRNRESSIEASLKPINDKKFLFF %%>%%Macrosiphum_euphorbiae-GAOM01007350hybGAOM01016471 MGAYVTWTLEVLAFAIFVVVAAVVPYVRRKRDYWTNRGVLAAAGYRSL ANTLPGVRLHDRSLSGHRNDAKAAGAAVLGLHDAGRPTALACDIRVAAAAMANDGFAEAE TRGGREMSLLPSAVDAGAVTAVLPTMAVCVAELITSLEAVANRRLTIMPWTEVKKCATTV VATCVYGQPMVDxxxGGRPTFTDHFASYDLSSDGRASSIDFKQILQAAAADSDKIGADVADKQVRLDMFEF VSGTIEQTAALVTGALYELARDQNIQNHLREHLDSVLDEHQEQVTIDQLDRLPYLENVLK ETLRKYPLAAVVRRVATKPYVVPGTGGRGTIEPDTLIVVPVHELHHDAEHFPEPEKFLPH RFPGQLSSAYMPHGSGPQSYIGKHFVELEAKLVIAMLMSRYEVHVDSSKSGTPPDPLDPK SFEGVRMTVANRSSVRESTMYASLRKFHMSNDMNAGDRKFLFF %%>%%Melanaphis_sacchari-XP_025205656-GFXV01005852 MGAYVTWTLEVLAFATFVVLAVLMPYARRKRDYWTNRGVPVAAGYRSLTNMLPGFRLHDRSLSRHRDDAKAAGATALGLFDGGRPTALACDLRVAAAALGNDGFTEAETTGGRETSLVPSAVDACAAIAVLPTMTVCVAELVTSLEAVANRRLTISPWTEVKNCATTVVATCVYGQPMVDSRIKTFAEQCDKALSDGGRGRPTITDYFASYDLSSDGRASSTDFKQIFRAAARCSDQIDADVADKQVRLDMFKFVTGTIEQTAALVTGVLYELANNQSIQNHLREHLDSELDEHQQQVTIDQLDRLPYLENVLKETLRKYPLVTVVCRMTTKSYVVPGTSGNGTIEPNTLIVVPVHALHHDAEHFSEPENFQPHRFPGQMSSAYMPYGSGSQSYIGKHFVELEAKLIVAMLVSRYEVHLDKDNPCTSPDSLDPRSFAGVRVTVVNRSGVREARMYTSLRQLHNDVVKNASDRKFLFF %%>%%Myzus_persicae-XP_022163875-CYP6YC1 MGSYVTWTLEALAFAIFVVFAAVVPYARRKLDYWTRRGLLAAAGYRSFASTLPGVRLQDRSLPGHRNDAK AAGAAVMGLYDAGRPTALACDIQVVAAAMANDGFAEVDTRGGQEMSLLPSAVDAGAVITVLPTMGVCVAE LITSLEAVANRRLTIMPWTEVKKCATTVVATCVYGQPMIDSRIKAFAEQCDKALSGGSGRPTLTDYFSSY DLSSDGRVSTSDFKKILRSAAADSDKIDADVADKQVRLDMFEFVTGTIEQTAALVTGALYELANDQDIQN HLREHLDGVLSEHQEQVTIDQLDRLPYLDNVLKETLRKYPLATAVRRVATKPYVVPGTGGRGTIEPDSLI VVPVHALHHDAEHFPEPEKFQPQRFPGQLSSAYMPHGSGPQSYIGKHFVELEAKLVLAMLVSRYEVIVDS TKPGTSPDPLEPRSFGGVRMTIANRSGVRESTMCASLRRFHMGDNENAGDRKFLFF %%>%%Rhopalosiphum_maidis XP_026823163 MGAYVTWTLEVLAFASFVVLAVLMPYARRKRDYWTSCGMPAASGYRSLANMLPGVRLHDRSLSRHRDDAK ATGAAALGLFDGGRPIALACDFRVAATALGNDGFAEAETTRVRETSLVPSAVDAGAVTAVLPTMAVCVAE LITSLEAVANRRLTISPWTEVKNCAMTVVATCVYGQPMVDSRIKAFAEQCKKALSGGGGRPTVTEYFASY DLPSNGRTSSTDFKQILMAAAANSDKIDADVADKQVRLDMFKFVTGTIEQTAALVTGVLYELAHNQNIQN HLREHLDSELDEHQQQVTIEQLDRLPYLENVLKETLRKYPLTTVVRRVATKPYVVPGTSGRGTIEPGSLI IVPVHALHHDAEHFSEPEEFQPHRFPGQLSSAYMPHGSGPQSYIGKHFVELEAKLIIATLVSRYEVHLDR DKPGTSPDSLDPRSFAGVRVTVANRSGVREPKMYTSLRQLHNSNDENASGRKFLFF %%>%%Schizaphis_graminum-GGMR01012494 MGAYVTWTLEVLAFAAFVVLAVLMPYARRKRDYWTSRGVLAAAGHRSLANT LPGVRLHGRSLSRHRDDAKAAGAAALGLFDGGRPVALACDFRVAATALGNDGFAEAETTR RVRETSLVPSAVDAGAVTAVLPTMAVCVAELVTSLEAVANRRLTISPWTEVNNCATTVVA TCVYGQPMVDSRIKAFAEQCKKALSGGGGRRPTVTDYFASYDLSSDGRTSSTDFKQIFME AAAANSDQIDADVADKQVRLDMFEFVTGTIEQTAALVTGVLYELAHNQNIQNHLREHLDS ELDEHQQQVTIDQLDRLPYLENVLKETLRKYPLATVVRRVATKPYVVPGTSGRGIIEPGS LIIVPVHALHHDAEHFPEPKQFQPHRFPGQLSSAYMPHGSGPQSYIGKHFVELEAKLIIA MLISRYEVHLDRDKPGMSPDSLDPRSFAGVRVTVANRSGVREPKMYTSLRQLHNSNDENA SGRKFLFF %%>%%Sipha_flava-XP_025412644-GGMS01015993 MGAYLMTLALEALAFAVFVALAAVVPYVRRKRGYWTSRGVTVATGARALAATVPGIRLDEKSLARYRDKAAAATLVGLHDAGRPCALACDVRVAAAALGNDGFIEPLGRTGAGSLIPRVVNAETVTAMLPAMCEAVTELITSLEALANLRQTIGPWTYAKKCSITTVATCVYGQPMIDSRVNAFAEQCDKALQRPAVTDYFTTYDLSSISGRGASSTDFKQLLREAAAADQNESSDVTDKQVRQDMFEFITGAIEPTAALVTAALYVLSRDQNIQDKLREHLDVVLDKHQQRITIDQLDRLTYLENVLEETLRKYPLVAVVRRLTTKSYVVPDGGQSVLEPGTLVAVPVHAFHHDQTHFTAPEMFLPDRFPGQLSSAYMPYGSGLRSHIGKHFVAVEVKLIIAMLVSRYAIHVDSDEPGRSPDPFDRTSFAGVRVKLTNHNGVKEPAMYESLRKCHRGNKKFLLFR %%>%%Sitobion_avenae-GAPL01021964 MGAYVTWTLEVLAFAIFVLVAAVVPYARRKRDY WTNRGVLAASGHRSLANTLPGFRLHDRSLSGHRNDAKAAGAAVLGLYDAGRPTALACDIR VAAAAMANDGFAEVETRGGRELSLLPSAVDAGAVTAVLPTMAVCVAELVTSLEAVANRRL TIVPWTEVKKCATTVVATCVYGQPMVDSLIKAFAEQCDKALSGAGGRPTVTDYFASYDLS SDGRASSSDFKQILRAAAADSDKIDADVADKQVRLDMFEFVTGTIEQTAALVTGALYELA RDQNIQNHLREHLDSVLDEHQEQITIDQLDRLPYLENVLKETLRKYPLAAVVRRVATKPY VVPGTGGRGTIEPDSLIVVPVHELHHDAEHFPEPEKFQPHRFPGQLSSAYMPHGSGPQSY IGKHFVELEAKLVIAMLMSRYEVHVDSAKPGSPPDPLDPKSFEGVRMTVANRSSVREWTM SASLRQFHMSNDANAGDRKFLFF