====== FASTA of the fourth type of P450 sequences lacking the conserved Cys ======

Type 4  - CYP3 clan,  Coleoptera (15 sequences)
Species / taxonomic position and accession number
(from Dermauw et al. 2020, Suppl. File S2) 



%%>%%Aethina_tumida-Coleoptera-Cucujoidea-XP_019871056
MDLCSRQFNFFVEASTLLYCLTLFTFVVVGLFLFVQSVYSFFEKQKIPRGPLPSPPFGNLKDVIFKRVNVNIHLWKYYNRFRRKKYWFGGLYILFKPLVMILDPYLVYTVLTDNNHFEDIDDDISEENASAIYDDAILVEFLKKYDALEDKFLNTIDSATSIYDFYVKASTHLIGISPLEFSTLEKKDHPRHQSTFSYYLSLSYPQLCQTFNINSNYGNTGLTNLLRKELERRKKNDIRKTDLLNNVSNANELNTDAYIKHISEFFFDSLEFGQSLTQFCLYELCENEDTQQELIGELRRFRKDNDVITRDNIAKLTLLDAIIKETLRKYPPHASIIRRCHKDYKNEKYRLNLLKECLTVVSVFGIHHDQLNFPNPEQFDPDRFYVENEKYMKSYSFIPFGVGAKSTIGMKFIVLQLKLCILSILSRYKVTLKSSSNLVYDPKKLTISPSSPLIFHFELL

%%>%%Anoplophora_chinensis-Coleoptera-Chrysomeloidea-Cerambycidae-GFXC01018943
MTGSCYYNQNSFFDYFEENKLISCITGFTFTVIFIFIYILKAYTFFDKRR
IPRAVDPTAPFGNIKDVLFQETTFYVYLWKYYNKFKRKGFKYGGLYLFFK
PSILVVDSIVMQKILTEEKCITDGHRNYFAKVSKVVNLFTEDNLENFLLR
YNRIKDTLLVDLDEKCTSTVLRNFFMETTSSAFGFKISVEALPAINALLN
KKTCSGFKYYFGLVYPLFERNKLVPEMQNLLKDVVEYRKKNDIRETDLIQ
SFIDLYNEGDYNLNEMVLGIFDIIVDNIIYSYSSLMFCLYELASNKDIQQ
NLIQEIERFNKQNKSVGLKALQQLSYLDAVVKETLRKYPPVPTIIKKCRE
CYKIDGTDLELPKGTFILHSVMGVHYDPLNYSDPGKFRPDRFLEEPNKVD
ISNVYIPFGLDKQKEIGFRFTVLHVKLGLISILSSYTVGMNSKSAMEFDN
KKVPIYPKEPLPIVFESILK

%%>%%Anoplophora_glabripennis-Coleoptera-Chrysomeloidea-Cerambycidae-AGLA000729-CYP413B1  
MTDSCYYNQNSFFDYFEENKLISCITGFTFTVIFIFIYILKAYTFFDKRCIPRAVDPTAPFGNIKDVLFQETTFYVYLWKYYNKFKRKGFKYGGLYLFFKPSILVVDSIVMQKILTEQKCITDGHRNYFPEVSTVVDLFTEDNLENFLLRYSSIK DTLLVDLDEKCASTVLHNFFMETTSSAFGFKISLEALPAINALLNKKTSSGFKYYLGLVYPALFERNKLVPEMQNLLKDIFEYRKKNDIRETDLIQSFIDLYNDGDYNLNDVILGIFDIIVDTIIYSYSSLMFCLYELASNKDIQKNLIQEIERFNKQNKSVGLKALRQLSYLDAVVKETLRKYPPVPTIIKKCKECYKIDGTNSELPKGTFILHSVMGVHYDPLNYSDPGKFRPDRFLEAPNKVDMSNVYIPFGLDKQKEIGFRFTVLHVKLGIISILSSYSVGMNSKSAMEFDNKKVPVYPKEPLPIVFESILK

%%>%%Callosobruchus_maculatus-Coleoptera-Chrysomeloidea-GEUE01020640
MSCTAAQPGILEAIASYIDEKTFFTTITSVTFAVLFLFLYILHAYTFFDK
NNIKDCATPAAPFGNLNDVIFHKDSWYMFLRKHYNRLKRKKLPFGGLYLF
FKPSILISDQILIERLILSQKENNEVLDTLFTKDVMQNTLEKIDSIYDEC
NELLNKQPCDRILNHFFVKTARLLFGFSIDDTKLENSMKGKSYSCFKHYL
GVAYSCFKSKNIYSHITASIQQELQNRKKNDIKHSDILHNLTKIDSNVIE
NLSEIFIENILFSTLSTMLCLYELSQDDTIQEELVGEIRRLFAKKGKMQF
QYLDHLPYMEAVVKETLRKWPPVPVEVIQNNQEVEGLPNNKNILLLLSIY
GMQNHPDNFVDPEQYDPDRFLEDNVRETLFMPFGIGPQRDINHRLTTMNI
KLALIWILSKYKVKIQPSYHLELDKTKVIIQPKVVVPLQFELID

%%>%%Colaphellus_bowringi-Coleoptera-Chrysomeloidea-Chrysomelinae-GBHN01003300
MSYCSPYSKGNILYYLDENKLFSCITTFTFVVIGIFWYILKCYTFFQRHKIPAAVR
PSAPYGNVEEVLCHNTNLYVYLWKYYNKFKRKGQKFGGFFVFLKPCILVVHPSVTFKVLS
EETVLEDAYRKRDLKHYRKVVKIFSDDLLEQILVKSSALKFSFMENGSFEKVLHYLVADL
TFLTFGFDKSLMAVLNAAGEKKTRSNFGHYLRLVLPLLQKRTSHRESRKIIKNTRVYRKK
LDIRENDVLQHFFDNAKDDDESEEILDEIIDIAVENNLQTFSSVLFSLYELAVNPEIQDD
LIGEIRRFNRDNRSLNLDNLHHMIYLEAVVKETLRKYPPVPLVVKRPKKNYDMSEFGVNI
PKNCLIFATIFGIHHDPANYADPESFDPDRFFEDNIKYIKPNTYLPFGLDSKKNIGFKLT
TVFIKLCIFNILSKYRVNLTNPDYTLEFDNHKLSTSPKQPLPLKFEMLDS

%%>%%Cucujus_clavipes-Coleoptera-Cucujoidea-GDNW01019926
MANSGLTNFLLDEHVLLYSLTLFTFIVIGIFIYIKNQVAFFDDRRIPRGP
LPSIPFGNIKDVLNHETPLFYHLWKFYNMFERKQFKYGGLCLFLKPSILF
VDPKLTEHILNEGKLLRDVISLKVSKKIAGVFREVIVIEFLRDHHEIEQK
LLESLEPGEVDINKKLCDFFIESTIRITGFEYDDVTRNLLQMSLEENNCL
SFKQYFCMCYPIFSKFLNVKRCSTNRNLLKKYVRECMNDRKKNDVRKLDL
IQALSDNFNNSEDESKTNYGIIDEFLQVVLDNLQNALAISLFGLFEVCSN
SEILEDLTGEIRRFKNDNKAINSTNLDNMVYLDTVVKETLRLFPPCPTIL
KVCQEKYQIPQGDLELPKGSFTIVSVYGIHYNESNFTIPNNFDPDRFAEQ
NKRYLKPQTFLPFGGDSNNIGMEFTTVFVKLAIIGMLSNFKITIPKKFGS
FREYDRKMLSPYPRKSVILKLEPIKKAI

%%>%%Dendroctonus_ponderosae-Coleoptera-Curculionidae-XP_019768810-CYP393A1 
MSFSNICLSEPFTFLNHINPHYLFYSIIIGTFASLFGLVWILKTYTYFEKQKVTRGSLPKFPFGNFREIIKENTSLHTFL
WKYYNKFKRKNLRFGGLFLLVRPVIVAVDPSAASNGTSLFPKECKLKPQEAAALLNHDVSNCFIKSFNSSVKAAIPETLLKSDAATVLKDYLLESTCLLFGFQAPQLVEEINELLEENFATSLKFYLRLCFPVLQKFQSPPKPHKRLLELMEARKKNDSEANDLIEAFTLLLNGSDYTVDDIAEEVFNAFLDTLSYSCSSLLFCFYELAINSETQQELIGEIRRFNQKNEALTCENLGRMEFLNATIKETFRKYPPVSTIIQQSKDLDWNPDKNGLILQSTLGIHRDPQFYTKPEAFEPDRFMDSIPVNEDTYLPFGVGAGSQLRMRLVSLQMALVLVGVFSHLKVGLRDGGAPFKYNSKLLYLSPSEGPHLEFSRI

%%>%%Hypothenemus_hampei-Coleoptera-Curculionidae-GDLS01015559-CYP393C1
MSNNICLTKHFTFLKYVNQHQMFYFLTLFTFAVLFALVWILRKYTTFEKLR
IPRASRPKFPYGNFSGVLKGETTLHIFLWKYHNRFKKKIYKYGGLFVFLKPVLLLTDVTV
AEELTQEKFLQICPKESKLTKDNVETILRTGALRTFIQKFQYSVNTAIPEKLLNSHTETV
IKEFLLESCCLAFGFKSFELLQEINELQQRYQISSKFYLFLTIPFFNRKKRKLCYDLEEY
FIDILEDRKKNDSEETDLLEAFINLYNESEIPVAGIAEELFDLFSDILNYSYSAIMFCLY
ELSNHKEIQDELIGEIRRHNNDKKSSAYDLLKLVYLDAVVKETFRKYPPVASIIKVGRKD
TGTLDWYPVKDPVIFQSVLGIQRDSEFYTKPEDFDPDRFSDNQVPKKGVYKPFGDGPASD
LRLKVASVQVKLMLHSILSSLRVEFKNDDCTLKYDPKLIYLSPGSDRINLKFLKIQY

%%>%%Lagria_hirta-Coleoptera-Tenebrionoidea-GDPQ01015519
MEQDWFLYSITLFTFSMIFLMCYIQHVFTYFQGKNIFLISQPTFPFGNVY
DVSFLQIPMFLKLWKYSNKLRRKLQPIGGFFIFLKPAVLVVDPQLSQKIL
NNSPDFENVAPSIEVSAELWDGITEKYLSDFRQSWQAINQHFDDNQINLS
SAMDDVIVECCIRKIFCINPNYSQKVKNSMQQQPFCDLLLLNYPNIIFGG
FLKNRKNLIPNNAFIDGENIFQNSFARESKSKADLFIQVLTILRSVNNLI
LLTLNEIAHSPRIQKSLREEIQSLKDEEYLEAVICEALRKYPPHPFIAKT
CKNDYKFDDRVVFEKNMLIFVSTFGIHYDQQYFMNPDEFQPSRFINSTNL
SSDNTRYFPFNRSATNDLELIYKRIMKTVLKEIVSNTKLSLSEKTPTLLK
FSEGIFQLKSKEDMWLKINKI

%%>%%Leptinotarsa_decemlineata-Coleoptera-Chrysomeloidea-XP_023025884-CYP413A1
MSYCSPYDKTSFLYYVDENKLFSGITFFTFAVIGVFCYILRCYSFFEKHKIPRAVTPSAPYGNIKDILFRNTTMYVFLWKYYNKFKRKGYKFAGFYLFFKPGILAVHPSLTFKILSDDRGFDNVSRKKNVLDYKKVLRMFDDSILQQLIESSNAIKPSLEEQLAGKTPLKEVLYGFLAESSCLTFGFNKGSADVLIKSADEKIRSGFWHYLKLVLSFTKSKSSNEDLRNFIKDVCGYRKKHDVREKDLLQCFTDTLRDDRESEGIIDEIIEIAIENIIYSCSTVLFCLYELASNPDIQDDLIGEIRRFNKNNSTINLDNLHHLIYLEAVVKETLRKYPPVPLVTKKPKEDYNMNDFGLDLPKSCLIFATIFGVHHDPANFPDPEAFDPDRFFEDNIKYIKPNTYFPFGLDSRNTIGFRLTNVHVELCIFNILSSFRVDLTKKDHVLEFDNDKLVTYPKEPLPLRFELLTN

%%>%%Meligethes_aeneus-Coleoptera-Nitidulidea-GAPE01037441-CYP3019A1 
MTFCDEEIKFFMKESTFIYCITSFTFLVVGFFILVQRAFSFFEKKGIPRGGVPRVPFGNVKDVIYQECNFNIHLWKYYNRFKRKKFHFAGLYILFKPFVMMMDPFLIYTVLTDKKHFQSQKDISKLFKDEIQDQLLEKYDTLEEIIYKSLVEKSYNLDYESLDAFFVETSSAILGLPITQNKKYSSNLLHYFSLCHESVWKIFTPNSSYNKNLKSQIANEILRRKKNDLRKFDLINSLSENNTSDFEEILDFCFDSMEYSKSITQFCLYELCQNSDIQQEIIGEVRRFRKDERKITRKNLNQLAILDATIKECLRKYPPRATIMKKCCEDFKNEKYKLNIPRHCMTVISVYGVHHDPMNFPNPEEFDPDRFYEENDKYLKSYSFVPFGDDENTEIYTKYIVLQVKLCLLTILSRYKVYLKNSCKLEFDCTKTTLSPKEPFVFNLEVLK

%%>%%Oreina_cacaliae-Coleoptera-Chrysomeloidea-GDPL01009582
MSYCNPYDKTSFLYYLDENKLLSWITSLTFAVIGIFWYILRCYGFFERHK
IPRAVTPSAPYGNVKDILFQNTTMYVFLWKYYNKFKRKGYKFAGFYLFLK
PGILVVHPSLTFKILSDDKVFEDVYRKKNVQDSKKVLRIFSDGILEQLIG
NSNTLKSNFLEKIGENLPLKEVLHSFLAESSCLTFGFENDFTDILIKKAE
EKICSSFCHYLRLVSPFLKRNSSQKEIQNFVKDTCRYRKKHDVREKDVLQ
CFIDTLEEDGESDGIIDEIIEIAVENIINSCSTVLFCLYELASNPDIQDD
LIGEIRRFNKYNSSINLENLHHLIYLEAVVKETLRKYPPVPLVTKKPKKD
YNMKDFGLDIPNNCLIFATIFGVHHDPANFPDPEAFDPDRFFEDNIKYIK
PNTYIPFGLDSRNSIGFRFTAVHVQLCIFNILSSFSVDLTNKSHMLEFDN
NKLVTYPKEPLPLRFELLSN

%%>%%Rhynchophorus_ferrugineus-Coleoptera-Curculionidae-GDKA01003140
MSLDDFCYEEKLPFVKYLNEKVLLYCITLLAFAGIFLLIWVIQNYTFFEK
AKILRGSLPKLPYGNLNNVVNKDNTIYEMLWKNYNRFKRKQCDIGGVFFF
TKPVVVVVKPEYIQEVLDNSDNFKQVFPEQVSQNIGEIFTSNSANSFIQK
YRESLRGVLSEKLQNYDFSTVLRSHLLEMASLAFGLNSPSLVEEINHILK
AKTDAKLKYHLGLCYPLLKSRNSSLYRNLNSLFVDITQARKTNDNSYDDI
IQYFMDFQRKSSTEPKIISRILFDLYADVLTHTYSVVFACFCELSKNEDV
QDELLGEIRRYNKKHSVMDIDSLKELEYLNAVVLETLRKYPPVPFILKIA
QKDFTLNNVQFPKGVLTAISILGIHRNPDNYTNPEDFDPDRFAEQTNSAF
LPFGNKIEENVFKLVVLFTKLLIIDTLTALKVSRKNDSNAVLKFDRNLIP
LRLSESYLLTFENL

%%>%%Sitophilus-oryzae-Coleoptera-Curculionidea-GEZY01019129
MDLESVCYEEKLPFLKYLNEKTLLYCITCLAFAGVFSLIWIVKKYTFFEK
AKLARVKTPRFPYGNISDVINKETTLYEVLGKYYSRFKKKGYDVGGMFFF
IKPVVIIVKNEYVRQILDSIENFSEVYPEQYKLKSDIFDSSCVKVFLENY
HVSLKGTILESLKKDDIHSVLRNYLLELVSLSFGVNSFEIIEELNLLLKL
KTEANFRYNLSLCHPIFKNKNSALYSDFEGVFLDIMNDRKKNDIVKDDFF
QFFINLFNESQCDTKEVSRELFNLFADSVIYSYSVILCSLYEMSRNTDIQ
DELIGEIRRYNKQGVVLNLDNLKELEYLNSVVFETLRKYPPVPYILKTCQ
KDFKKNNLVVPKDTLVAVSILGLHRSSENYTDPENFDPDRFADQSDLNKV
LYIPFGTRRRGNLTKLVILYTKLTLVDIFSNLTVRKKKDSEQIFKFDPML
IPLRPMETYPFVFDRL 

%%>%%Tribolium_castaneum-Coleoptera-Tenebrionoidea-NP_001164359-CYP348A1
MEQDWFFYSVTLFTFAVIFTFCYIRHVYTFFERKRIPRAGHPTFPFGNLYDVFFEKVPIFMQLWKFYNRFKRKKCKLGGFYLFLKPAIVLVDTTLVQLFFTDVFAKDERDDLDANFCGQVLASVVKSVEKVWPKLGPFAENEANFTQILGQELVGLCAREFFDSNDAKLCEVEGSRVFPLFRKCVSLSYPQFCKNENHRFRGKNFEKAAKNGVLQVLQKNGFSAKDRVDFIAELVDYLGKSSNLILFTLYELSLNREIQDDLRGEILRFRRNKDTFTYTELEQLTYLETVICETLRKYPMKPFVHKVCQKTFEQNGIKFDTNQTVFLSIFGIHHDVDNYINPELFDPDRFSEENEMFIDPIKYLPFGHQIKNDFDSLYAKLIMKMILIELLSKYEFALGKKSPKCITFDENLFEIKSREDMWLKIKKL