====== P450 redox partners ====== The reducing equivalents from NADPH are transferred to P450 enzymes from two types of redox partners: (a) for microsomal P450s, from [[reductase|NADPH cytochrome P450 reductase ]], with in some cases a contribution from [[b5|cytochrome b5]] and (b) for mitochondrial P450s, from insect orthologs of [[adrenodoxin|adrenodoxin]] and [[adrenodoxin|adrenodoxin reductase]]. These two types of redox partners have been functionally demonstrated in insects, and operate as shown below: {{ ::redox_partners.jpg?600 |}}