FASTA of the fourth type of P450 sequences lacking the conserved Cys

Type 4 - CYP3 clan, Coleoptera (15 sequences) Species / taxonomic position and accession number (from Dermauw et al. 2020, Suppl. File S2)

>Aethina_tumida-Coleoptera-Cucujoidea-XP_019871056 MDLCSRQFNFFVEASTLLYCLTLFTFVVVGLFLFVQSVYSFFEKQKIPRGPLPSPPFGNLKDVIFKRVNVNIHLWKYYNRFRRKKYWFGGLYILFKPLVMILDPYLVYTVLTDNNHFEDIDDDISEENASAIYDDAILVEFLKKYDALEDKFLNTIDSATSIYDFYVKASTHLIGISPLEFSTLEKKDHPRHQSTFSYYLSLSYPQLCQTFNINSNYGNTGLTNLLRKELERRKKNDIRKTDLLNNVSNANELNTDAYIKHISEFFFDSLEFGQSLTQFCLYELCENEDTQQELIGELRRFRKDNDVITRDNIAKLTLLDAIIKETLRKYPPHASIIRRCHKDYKNEKYRLNLLKECLTVVSVFGIHHDQLNFPNPEQFDPDRFYVENEKYMKSYSFIPFGVGAKSTIGMKFIVLQLKLCILSILSRYKVTLKSSSNLVYDPKKLTISPSSPLIFHFELL

>Anoplophora_chinensis-Coleoptera-Chrysomeloidea-Cerambycidae-GFXC01018943 MTGSCYYNQNSFFDYFEENKLISCITGFTFTVIFIFIYILKAYTFFDKRR IPRAVDPTAPFGNIKDVLFQETTFYVYLWKYYNKFKRKGFKYGGLYLFFK PSILVVDSIVMQKILTEEKCITDGHRNYFAKVSKVVNLFTEDNLENFLLR YNRIKDTLLVDLDEKCTSTVLRNFFMETTSSAFGFKISVEALPAINALLN KKTCSGFKYYFGLVYPLFERNKLVPEMQNLLKDVVEYRKKNDIRETDLIQ SFIDLYNEGDYNLNEMVLGIFDIIVDNIIYSYSSLMFCLYELASNKDIQQ NLIQEIERFNKQNKSVGLKALQQLSYLDAVVKETLRKYPPVPTIIKKCRE CYKIDGTDLELPKGTFILHSVMGVHYDPLNYSDPGKFRPDRFLEEPNKVD ISNVYIPFGLDKQKEIGFRFTVLHVKLGLISILSSYTVGMNSKSAMEFDN KKVPIYPKEPLPIVFESILK

>Anoplophora_glabripennis-Coleoptera-Chrysomeloidea-Cerambycidae-AGLA000729-CYP413B1 MTDSCYYNQNSFFDYFEENKLISCITGFTFTVIFIFIYILKAYTFFDKRCIPRAVDPTAPFGNIKDVLFQETTFYVYLWKYYNKFKRKGFKYGGLYLFFKPSILVVDSIVMQKILTEQKCITDGHRNYFPEVSTVVDLFTEDNLENFLLRYSSIK DTLLVDLDEKCASTVLHNFFMETTSSAFGFKISLEALPAINALLNKKTSSGFKYYLGLVYPALFERNKLVPEMQNLLKDIFEYRKKNDIRETDLIQSFIDLYNDGDYNLNDVILGIFDIIVDTIIYSYSSLMFCLYELASNKDIQKNLIQEIERFNKQNKSVGLKALRQLSYLDAVVKETLRKYPPVPTIIKKCKECYKIDGTNSELPKGTFILHSVMGVHYDPLNYSDPGKFRPDRFLEAPNKVDMSNVYIPFGLDKQKEIGFRFTVLHVKLGIISILSSYSVGMNSKSAMEFDNKKVPVYPKEPLPIVFESILK

>Callosobruchus_maculatus-Coleoptera-Chrysomeloidea-GEUE01020640 MSCTAAQPGILEAIASYIDEKTFFTTITSVTFAVLFLFLYILHAYTFFDK NNIKDCATPAAPFGNLNDVIFHKDSWYMFLRKHYNRLKRKKLPFGGLYLF FKPSILISDQILIERLILSQKENNEVLDTLFTKDVMQNTLEKIDSIYDEC NELLNKQPCDRILNHFFVKTARLLFGFSIDDTKLENSMKGKSYSCFKHYL GVAYSCFKSKNIYSHITASIQQELQNRKKNDIKHSDILHNLTKIDSNVIE NLSEIFIENILFSTLSTMLCLYELSQDDTIQEELVGEIRRLFAKKGKMQF QYLDHLPYMEAVVKETLRKWPPVPVEVIQNNQEVEGLPNNKNILLLLSIY GMQNHPDNFVDPEQYDPDRFLEDNVRETLFMPFGIGPQRDINHRLTTMNI KLALIWILSKYKVKIQPSYHLELDKTKVIIQPKVVVPLQFELID

>Colaphellus_bowringi-Coleoptera-Chrysomeloidea-Chrysomelinae-GBHN01003300 MSYCSPYSKGNILYYLDENKLFSCITTFTFVVIGIFWYILKCYTFFQRHKIPAAVR PSAPYGNVEEVLCHNTNLYVYLWKYYNKFKRKGQKFGGFFVFLKPCILVVHPSVTFKVLS EETVLEDAYRKRDLKHYRKVVKIFSDDLLEQILVKSSALKFSFMENGSFEKVLHYLVADL TFLTFGFDKSLMAVLNAAGEKKTRSNFGHYLRLVLPLLQKRTSHRESRKIIKNTRVYRKK LDIRENDVLQHFFDNAKDDDESEEILDEIIDIAVENNLQTFSSVLFSLYELAVNPEIQDD LIGEIRRFNRDNRSLNLDNLHHMIYLEAVVKETLRKYPPVPLVVKRPKKNYDMSEFGVNI PKNCLIFATIFGIHHDPANYADPESFDPDRFFEDNIKYIKPNTYLPFGLDSKKNIGFKLT TVFIKLCIFNILSKYRVNLTNPDYTLEFDNHKLSTSPKQPLPLKFEMLDS

>Cucujus_clavipes-Coleoptera-Cucujoidea-GDNW01019926 MANSGLTNFLLDEHVLLYSLTLFTFIVIGIFIYIKNQVAFFDDRRIPRGP LPSIPFGNIKDVLNHETPLFYHLWKFYNMFERKQFKYGGLCLFLKPSILF VDPKLTEHILNEGKLLRDVISLKVSKKIAGVFREVIVIEFLRDHHEIEQK LLESLEPGEVDINKKLCDFFIESTIRITGFEYDDVTRNLLQMSLEENNCL SFKQYFCMCYPIFSKFLNVKRCSTNRNLLKKYVRECMNDRKKNDVRKLDL IQALSDNFNNSEDESKTNYGIIDEFLQVVLDNLQNALAISLFGLFEVCSN SEILEDLTGEIRRFKNDNKAINSTNLDNMVYLDTVVKETLRLFPPCPTIL KVCQEKYQIPQGDLELPKGSFTIVSVYGIHYNESNFTIPNNFDPDRFAEQ NKRYLKPQTFLPFGGDSNNIGMEFTTVFVKLAIIGMLSNFKITIPKKFGS FREYDRKMLSPYPRKSVILKLEPIKKAI

>Dendroctonus_ponderosae-Coleoptera-Curculionidae-XP_019768810-CYP393A1 MSFSNICLSEPFTFLNHINPHYLFYSIIIGTFASLFGLVWILKTYTYFEKQKVTRGSLPKFPFGNFREIIKENTSLHTFL WKYYNKFKRKNLRFGGLFLLVRPVIVAVDPSAASNGTSLFPKECKLKPQEAAALLNHDVSNCFIKSFNSSVKAAIPETLLKSDAATVLKDYLLESTCLLFGFQAPQLVEEINELLEENFATSLKFYLRLCFPVLQKFQSPPKPHKRLLELMEARKKNDSEANDLIEAFTLLLNGSDYTVDDIAEEVFNAFLDTLSYSCSSLLFCFYELAINSETQQELIGEIRRFNQKNEALTCENLGRMEFLNATIKETFRKYPPVSTIIQQSKDLDWNPDKNGLILQSTLGIHRDPQFYTKPEAFEPDRFMDSIPVNEDTYLPFGVGAGSQLRMRLVSLQMALVLVGVFSHLKVGLRDGGAPFKYNSKLLYLSPSEGPHLEFSRI

>Hypothenemus_hampei-Coleoptera-Curculionidae-GDLS01015559-CYP393C1 MSNNICLTKHFTFLKYVNQHQMFYFLTLFTFAVLFALVWILRKYTTFEKLR IPRASRPKFPYGNFSGVLKGETTLHIFLWKYHNRFKKKIYKYGGLFVFLKPVLLLTDVTV AEELTQEKFLQICPKESKLTKDNVETILRTGALRTFIQKFQYSVNTAIPEKLLNSHTETV IKEFLLESCCLAFGFKSFELLQEINELQQRYQISSKFYLFLTIPFFNRKKRKLCYDLEEY FIDILEDRKKNDSEETDLLEAFINLYNESEIPVAGIAEELFDLFSDILNYSYSAIMFCLY ELSNHKEIQDELIGEIRRHNNDKKSSAYDLLKLVYLDAVVKETFRKYPPVASIIKVGRKD TGTLDWYPVKDPVIFQSVLGIQRDSEFYTKPEDFDPDRFSDNQVPKKGVYKPFGDGPASD LRLKVASVQVKLMLHSILSSLRVEFKNDDCTLKYDPKLIYLSPGSDRINLKFLKIQY

>Lagria_hirta-Coleoptera-Tenebrionoidea-GDPQ01015519 MEQDWFLYSITLFTFSMIFLMCYIQHVFTYFQGKNIFLISQPTFPFGNVY DVSFLQIPMFLKLWKYSNKLRRKLQPIGGFFIFLKPAVLVVDPQLSQKIL NNSPDFENVAPSIEVSAELWDGITEKYLSDFRQSWQAINQHFDDNQINLS SAMDDVIVECCIRKIFCINPNYSQKVKNSMQQQPFCDLLLLNYPNIIFGG FLKNRKNLIPNNAFIDGENIFQNSFARESKSKADLFIQVLTILRSVNNLI LLTLNEIAHSPRIQKSLREEIQSLKDEEYLEAVICEALRKYPPHPFIAKT CKNDYKFDDRVVFEKNMLIFVSTFGIHYDQQYFMNPDEFQPSRFINSTNL SSDNTRYFPFNRSATNDLELIYKRIMKTVLKEIVSNTKLSLSEKTPTLLK FSEGIFQLKSKEDMWLKINKI

>Leptinotarsa_decemlineata-Coleoptera-Chrysomeloidea-XP_023025884-CYP413A1 MSYCSPYDKTSFLYYVDENKLFSGITFFTFAVIGVFCYILRCYSFFEKHKIPRAVTPSAPYGNIKDILFRNTTMYVFLWKYYNKFKRKGYKFAGFYLFFKPGILAVHPSLTFKILSDDRGFDNVSRKKNVLDYKKVLRMFDDSILQQLIESSNAIKPSLEEQLAGKTPLKEVLYGFLAESSCLTFGFNKGSADVLIKSADEKIRSGFWHYLKLVLSFTKSKSSNEDLRNFIKDVCGYRKKHDVREKDLLQCFTDTLRDDRESEGIIDEIIEIAIENIIYSCSTVLFCLYELASNPDIQDDLIGEIRRFNKNNSTINLDNLHHLIYLEAVVKETLRKYPPVPLVTKKPKEDYNMNDFGLDLPKSCLIFATIFGVHHDPANFPDPEAFDPDRFFEDNIKYIKPNTYFPFGLDSRNTIGFRLTNVHVELCIFNILSSFRVDLTKKDHVLEFDNDKLVTYPKEPLPLRFELLTN

>Meligethes_aeneus-Coleoptera-Nitidulidea-GAPE01037441-CYP3019A1 MTFCDEEIKFFMKESTFIYCITSFTFLVVGFFILVQRAFSFFEKKGIPRGGVPRVPFGNVKDVIYQECNFNIHLWKYYNRFKRKKFHFAGLYILFKPFVMMMDPFLIYTVLTDKKHFQSQKDISKLFKDEIQDQLLEKYDTLEEIIYKSLVEKSYNLDYESLDAFFVETSSAILGLPITQNKKYSSNLLHYFSLCHESVWKIFTPNSSYNKNLKSQIANEILRRKKNDLRKFDLINSLSENNTSDFEEILDFCFDSMEYSKSITQFCLYELCQNSDIQQEIIGEVRRFRKDERKITRKNLNQLAILDATIKECLRKYPPRATIMKKCCEDFKNEKYKLNIPRHCMTVISVYGVHHDPMNFPNPEEFDPDRFYEENDKYLKSYSFVPFGDDENTEIYTKYIVLQVKLCLLTILSRYKVYLKNSCKLEFDCTKTTLSPKEPFVFNLEVLK

>Oreina_cacaliae-Coleoptera-Chrysomeloidea-GDPL01009582 MSYCNPYDKTSFLYYLDENKLLSWITSLTFAVIGIFWYILRCYGFFERHK IPRAVTPSAPYGNVKDILFQNTTMYVFLWKYYNKFKRKGYKFAGFYLFLK PGILVVHPSLTFKILSDDKVFEDVYRKKNVQDSKKVLRIFSDGILEQLIG NSNTLKSNFLEKIGENLPLKEVLHSFLAESSCLTFGFENDFTDILIKKAE EKICSSFCHYLRLVSPFLKRNSSQKEIQNFVKDTCRYRKKHDVREKDVLQ CFIDTLEEDGESDGIIDEIIEIAVENIINSCSTVLFCLYELASNPDIQDD LIGEIRRFNKYNSSINLENLHHLIYLEAVVKETLRKYPPVPLVTKKPKKD YNMKDFGLDIPNNCLIFATIFGVHHDPANFPDPEAFDPDRFFEDNIKYIK PNTYIPFGLDSRNSIGFRFTAVHVQLCIFNILSSFSVDLTNKSHMLEFDN NKLVTYPKEPLPLRFELLSN

>Rhynchophorus_ferrugineus-Coleoptera-Curculionidae-GDKA01003140 MSLDDFCYEEKLPFVKYLNEKVLLYCITLLAFAGIFLLIWVIQNYTFFEK AKILRGSLPKLPYGNLNNVVNKDNTIYEMLWKNYNRFKRKQCDIGGVFFF TKPVVVVVKPEYIQEVLDNSDNFKQVFPEQVSQNIGEIFTSNSANSFIQK YRESLRGVLSEKLQNYDFSTVLRSHLLEMASLAFGLNSPSLVEEINHILK AKTDAKLKYHLGLCYPLLKSRNSSLYRNLNSLFVDITQARKTNDNSYDDI IQYFMDFQRKSSTEPKIISRILFDLYADVLTHTYSVVFACFCELSKNEDV QDELLGEIRRYNKKHSVMDIDSLKELEYLNAVVLETLRKYPPVPFILKIA QKDFTLNNVQFPKGVLTAISILGIHRNPDNYTNPEDFDPDRFAEQTNSAF LPFGNKIEENVFKLVVLFTKLLIIDTLTALKVSRKNDSNAVLKFDRNLIP LRLSESYLLTFENL

>Sitophilus-oryzae-Coleoptera-Curculionidea-GEZY01019129 MDLESVCYEEKLPFLKYLNEKTLLYCITCLAFAGVFSLIWIVKKYTFFEK AKLARVKTPRFPYGNISDVINKETTLYEVLGKYYSRFKKKGYDVGGMFFF IKPVVIIVKNEYVRQILDSIENFSEVYPEQYKLKSDIFDSSCVKVFLENY HVSLKGTILESLKKDDIHSVLRNYLLELVSLSFGVNSFEIIEELNLLLKL KTEANFRYNLSLCHPIFKNKNSALYSDFEGVFLDIMNDRKKNDIVKDDFF QFFINLFNESQCDTKEVSRELFNLFADSVIYSYSVILCSLYEMSRNTDIQ DELIGEIRRYNKQGVVLNLDNLKELEYLNSVVFETLRKYPPVPYILKTCQ KDFKKNNLVVPKDTLVAVSILGLHRSSENYTDPENFDPDRFADQSDLNKV LYIPFGTRRRGNLTKLVILYTKLTLVDIFSNLTVRKKKDSEQIFKFDPML IPLRPMETYPFVFDRL

>Tribolium_castaneum-Coleoptera-Tenebrionoidea-NP_001164359-CYP348A1 MEQDWFFYSVTLFTFAVIFTFCYIRHVYTFFERKRIPRAGHPTFPFGNLYDVFFEKVPIFMQLWKFYNRFKRKKCKLGGFYLFLKPAIVLVDTTLVQLFFTDVFAKDERDDLDANFCGQVLASVVKSVEKVWPKLGPFAENEANFTQILGQELVGLCAREFFDSNDAKLCEVEGSRVFPLFRKCVSLSYPQFCKNENHRFRGKNFEKAAKNGVLQVLQKNGFSAKDRVDFIAELVDYLGKSSNLILFTLYELSLNREIQDDLRGEILRFRRNKDTFTYTELEQLTYLETVICETLRKYPMKPFVHKVCQKTFEQNGIKFDTNQTVFLSIFGIHHDVDNYINPELFDPDRFSEENEMFIDPIKYLPFGHQIKNDFDSLYAKLIMKMILIELLSKYEFALGKKSPKCITFDENLFEIKSREDMWLKIKKL