Differences

This shows you the differences between two versions of the page.

--- altsplicing [2025/08/11 08:46] – renefeyereisen
+++ altsplicing [2025/10/21 12:36] (current) – renefeyereisen
@@ Line 5: / Line 5: @@
 Alternative splicing of human P450s has been well documented [[http://dx.doi.org/10.1124/dmd.116.073254|(Annalora et al.,2017)]].
-The nomenclature rules for alternatively spliced P450s follows Nelson et al. (2004), where the locus is named and the alternatively spliced exons named with the _v#a and _v#b suffixes.
+The nomenclature rules for alternatively spliced P450s follows Nelson et al. (2004), where the locus is named and the alternatively spliced exons named with the _v#a and _v#b suffixes. Here # is the number of the coding exon and a, b, c... follow the order of the exons on the chromosome.
 Thus in //[[drosophila|Drosophila melanogaster]]//, alternative splice forms of CYP4D1 are known (Tijet et al., 2001; Chung et al., 2009; Good et al., 2014). They differ by their first exon and should be named CYP4D1_v1a and CYP4D1_v1b