The cytochrome P450 gene family (CYP genes) of arthropods encodes diverse enzymes involved in the metabolism of foreign compounds (xenobiotics) and in essential endocrine or ecophysiological functions.

This is a dokuwiki with focus on arthropod P450s (for the regular wikipedia page, seeCytochrome_P450)

* CYP genes, P450 enzymes A short introduction with notes on nomenclature

* CYP clans CYP families are grouped by clans. With lookup tables of CYP families by clan, and CYPome compositions by clans

* P450 sequences Collection of manually curated arthropod CYPomes

* P450 structure Short description of P450 primary and secondary structures

* P450 catalysis How P450s work

* Redox partners The proteins that transfer reducing equivalents from NADPH

* P450 functions What is known about what P450s do

* P450 and resistance

* Bibliography

* chemical structures The most commonly cited chemicals in this wiki

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Interpretations and generalizations are those of the contributors, and may change with new information. A selected bibliography is provided in the menu. Not ALL publications on arthropod P450s are listed. For some key papers, a direct link is also provided when cited.

The web version of this dokuwiki has been made possible by Jason Charamis. We thank the Director of the IMBB, Prof. John Vontas, for hosting this site on an IMBB server.

NOTICE : This is a chatGPT-free site. Nothing here to follow, like, or twitter about. Not meant for sordid bots, narcissistic influencers, asocial media or other parasites of scholarship.