p450_and_resistance
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| p450_and_resistance [2026/02/25 16:50] – renefeyereisen | p450_and_resistance [2026/02/25 16:52] (current) – renefeyereisen | ||
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| ==== UP-regulation of P450 expression ==== | ==== UP-regulation of P450 expression ==== | ||
| - | The expression of P450 genes in wild-type, susceptible populations is [[regulation|regulated]] by complex mechanisms that involve both the gene itself, and diffusible factors from elsewhere in the cell. Mutations in those mechanisms that cause constitutive UP (or DOWN) regulation of the gene can be selected, thus contributing to resistance. | + | The expression of P450 genes in wild-type, susceptible populations is regulated by complex mechanisms that involve both the gene itself, and diffusible factors from elsewhere in the cell. Mutations in those mechanisms that cause constitutive UP (or DOWN) regulation of the gene can be selected, thus contributing to resistance. |
p450_and_resistance.txt · Last modified: by renefeyereisen