Human CYPome 57 human P450s

Saccharomyces cerevisiae CYPome 3 yeast P450s

Arabidopsis thaliana CYPome 244 Arabidopsis P450s

Escherichia coli is a major model organism lacking P450 genes. The distribution of P450s in bacteria is highly uneven, for instance all cyanobacteria and mycobacteria have P450 genes, most firmicutes, bacteroidetes and gammaproteobacterial species have none (Nkosi et al. 2022).